Hexylamine → N-Hexyl-1-methyl-4,5-diphenyl-1H-imidazole-2-carboxamide

HRID 1828566Notes

Reaction equation

HRID 1828566 reaction equation
[CH2:1]([NH2:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[C:8]1([C:14]2[N:15]=[C:16]([C:26](O)=[O:27])[N:17]([CH3:25])[C:18]=2[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[CH2:1]([NH:7][C:26]([C:16]1[N:17]([CH3:25])[C:18]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[C:14]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:15]=1)=[O:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

3

Reactant 2

HCID 8102HexylamineHCID 22066062HCID 22066062, compound

Product 1

HCID 9968913N-Hexyl-1-methyl-4,5-diphenyl-1H-imidazole-2-carboxamide

Procedure

Using essentially the same procedure as Example 4, Step B, but using n-hexylamine (0.025 mL), 4,5-diphenyl-1-methylimidazole-2-carboxylic acid (30 mg, 0.10 mmol) from Example 4, Step A was converted to the title compound.

Sources & evidence

ORD record
ord-34e627af6bcf4b0bad4cea3fb39ed37c
Source dataset
uspto-grants-2006_06
Patent number
US07057051B2

Reaction notes

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