Benzylamine → HCID 10178830, compound

HRID 1828571Notes

Reaction equation

HRID 1828571 reaction equation
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[N:17]=[C:18]([C:29](O)=[O:30])[N:19]([CH3:28])[C:20]=2[C:21]2[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=2)=[CH:12][CH:11]=1>>[CH2:1]([NH:8][C:29]([C:18]1[N:19]([CH3:28])[C:20]([C:21]2[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=2)=[C:16]([C:13]2[CH:12]=[CH:11][C:10]([CH3:9])=[CH:15][CH:14]=2)[N:17]=1)=[O:30])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 22066080HCID 22066080, compound

Product 1

HCID 10178830HCID 10178830, compound

Procedure

Using essentially the same procedure as Example 9, Step B, but using benzylamine (0.022 mL), 4,5-di-(4-methylphenyl)-1-methylimidazole-2-carboxylic acid (25 mg, 0.08 mmol) from Example 9, Step A was converted to the title compound. HPLC/MS: 396 (M+1); Rt=4.13 min.

Sources & evidence

ORD record
ord-6c2ea041441c4ed3bd80956717c3032a
Source dataset
uspto-grants-2006_06
Patent number
US07057051B2

Reaction notes

Loading…