tert-Butyl 3-aminopropanoate → HCID 69136002, compound

HRID 1828699Notes

Reaction equation

HRID 1828699 reaction equation
Br[CH2:2][C:3]1[CH:26]=[CH:25][C:6]([CH2:7][S:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[C:11]([C:21]([F:24])([F:23])[F:22])[CH:10]=2)=[CH:5][CH:4]=1.[C:27]([O:31][C:32](=[O:36])[CH2:33][CH2:34][NH2:35])([CH3:30])([CH3:29])[CH3:28]>>[C:27]([O:31][C:32](=[O:36])[CH2:33][CH2:34][NH:35][CH2:2][C:3]1[CH:26]=[CH:25][C:6]([CH2:7][S:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[C:11]([C:21]([F:24])([F:23])[F:22])[CH:10]=2)=[CH:5][CH:4]=1)([CH3:30])([CH3:29])[CH3:28]

Participants

3

Reactant 2

HCID 4192171tert-Butyl 3-aminopropanoateHCID 22057733HCID 22057733, compound

Product 1

HCID 69136002HCID 69136002, compound

Procedure

3-[4-(2-Trifluoromethyl-biphenyl-4-ylsulfanylmethyl)-benzylamino]-propionic acid tert-butyl ester is synthesized similarly as described above by reaction of 4-(4-bromomethyl-benzylsulfanyl)-2-trifluoromethyl-biphenyl with 3-amino-propionic acid tert-butyl ester.

Sources & evidence

ORD record
ord-e242d5bba7fd4e48bee1d0ec452f83bb
Source dataset
uspto-grants-2006_06
Patent number
US07060697B2

Reaction notes

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