P-Anisidine → HCID 178492222, compound

HRID 1828892Notes

Reaction equation

HRID 1828892 reaction equation
[NH2:1][C:2]1[CH2:6][C:5](=[O:7])[NH:4][N:3]=1.[CH3:8][O:9][C:10]1[CH:16]=[CH:15][C:13](N)=[CH:12][CH:11]=1>C(O)(=O)C>[CH3:8][O:9][C:10]1[CH:16]=[CH:15][C:13]([NH:1][C:2]2[CH2:6][C:5](=[O:7])[NH:4][N:3]=2)=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 7732P-AnisidineHCID 735385-Imino-4,5-dihydro-1H-pyrazol-3-ol

Product 1

HCID 178492222HCID 178492222, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 3-amino-2-pyrazolin-5-one (20 mmol), 4-methoxyaniline (25 mol) in 50 ml of acetic acid was refluxed for 4 hours. The solvent was evaporated, the residue was suspended in water. The solid was filtered and crystallized from methanol.

Workup

  1. temperaturewas refluxed for 4 hours
  2. customThe solvent was evaporated
  3. filtrationThe solid was filtered
  4. customcrystallized from methanol

Sources & evidence

ORD record
ord-37d20950e35341e88033d86044f315ff
Source dataset
uspto-grants-2006_06
Patent number
US07060822B1

Reaction notes

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