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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 182926Generated: October 25, 2026

Hydroxide → methyl 7-((1R,2R,3R,5S)-5-acetoxy-2-((E)-4,4-difluoro-3-oxooct-1-en-1-yl)-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoate

https://huagongshe.com/reaction/182926

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantDimethyl (3,3-difluoro-2-oxoheptyl)phosphonateHCID 11118722—
ReactantHCID 13018123HCID 13018123—
Productmethyl 7-((1R,2R,3R,5S)-5-acetoxy-2-((E)-4,4-difluoro-3-oxooct-1-en-1-yl)-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoateHCID 72300959—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-ad5002acaffb44418aaa9d9ca6f0300b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)