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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 182942Generated: October 31, 2026

Ethanolamine → 6-chloro-4'-{5-chloro-2-[1-(2-hydroxy-ethylcarbamoyl)-1-methyl-ethoxy]-phenyl}-2'-(5-fluoro-2-methyl-phenyl)-spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

https://huagongshe.com/reaction/182942

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
ReactantTetrahydrofuranHCID 8028—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant6-chloro-4'-[5-chloro-2-(2-hydroxy-1,1-dimethyl-ethoxy)phenyl]-2'-[5-fluoro-2-methylphenyl]spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 76567885—
Product6-chloro-4'-{5-chloro-2-[1-(2-hydroxy-ethylcarbamoyl)-1-methyl-ethoxy]-phenyl}-2'-(5-fluoro-2-methyl-phenyl)-spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 74928685—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-2438a08d347c4d1aa145a8f80856c88c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)