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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1829592Generated: October 30, 2026

Propylene Oxide → 2-(1-Cyclohexylpropoxy)-2-methylpropyl propionate

https://huagongshe.com/reaction/1829592

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylene OxideHCID 6378—
ReactantAcetic AnhydrideHCID 7918—
ReactantPropionic anhydrideHCID 31263—
ReactantCyclohexanemethanol, alpha,alpha-dimethyl-HCID 85531—
Reactant1-CyclohexylethanolHCID 137829—
ReactantHCID 178478990HCID 178478990—
SolventAcetoneHCID 180—
Product2-(1-Cyclohexylpropoxy)-2-methylpropyl propionateHCID 68435557—

Reaction Steps

The following compounds of Examples 6 and 7 were prepared analogously to the methods described under Example 1, except that the alcohol component used was 2-cyclohexyl-2-propanol, which can be prepared from cyclohexylmagnesium chloride and acetone by a Grignard reaction, instead of 1-cyclohexyl-1-ethanol. Furthermore, propylene oxide was used instead of isobutylene oxide. The esterification was carried out with acetic anhydride (Example 6) or propionic anhydride (Example 7). Thus, only the spectroscopic data are given at this point:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07064102B2
Source datasetuspto-grants-2006_06
ORD IDord-49d23bbc67fc4dd8ac83b1cac993692c
Source noteuspto-grants-2006_06