HCID 11181172, compound → HCID 11773714, compound

Participants

Reaction Steps

A solution of 3α-(t-butyldiphenylsilyloxy)-17β-[2-(4-tolyl)ethynyl]-5α-androstane (80 mg, 0.13 mmol) in anhydrous tetrahydrofuran (5.2 mL) was treated with a 1M solution of (n-Bu)4N+F− (2.6 mL, 2.6 mmol) and the resulting solution was stirred at RT for 48 h. Work up of the reaction was accomplished as in Example 2. Purification by flash column chromatography using dichloromethane as eluent afforded the desired product named above.

Provenance & Evidence