MAGNESIUM SILICATE (synthetic) → HCID 86600184, compound

Participants

Reaction Steps

Pyridinium chlorochromate (22 mg, 0.10 mmol) was added to anhydrous methylene chloride (1 mL) and to the resulting mixture was added a solution of 4[3α-(t-butyldiphenylsilyloxy)-5α-androstan-17β-yl]-3-butyn-2-ol (30 mg, 0.053 mmol) in dichloromethane (2.5 mL) and the resulting mixture was stirred for 3 h at RT. Subsequently the mixture was fitered through florisil, washed with ether and the solvent was removed in vavuo. Purification of the residue using flash column chromatography, petroleum ether/ethyl acetate 97/3 elution solvent, afforded the product mentioned above.

Provenance & Evidence