HCID 69592544, compound → HCID 87903204, compound

Participants

Reaction Steps

A solution of (n-Bu)4N+F− 1M in THF (0.72 mL, 0.72 mmol) was added to a solution of 3-trimethylsilyl-1-[3α-(t-butyidiphenylsilyloxy)-5α-androstan-17β-yl]-2-propyn-1-ol (310 mg, 0.48 mmol) in THF (10 mL) and the resulting mixture was stirred at RT for 30 min. The reaction mixture was worked up as in Example 7 to afford after purification by flash column chromatography using petroleum ether/acetone 82/18 as elution solvent the compound named above.

Provenance & Evidence