HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetamidopyrrolidine → HCID 22053561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetamidopyrrolidine | HCID 522715 | — |
| Reactant | 6-[3,5-Bis(trifluoromethyl)benzyl]-5,6,7,8,9,10-hexahydro-4-(2-methylphenyl)-2-(methylsulfonyl)-5-oxopyrimido[4,5-b][1,5]diazocine | HCID 22053591 | — |
| Product | HCID 22053561 | HCID 22053561 | 99.5% |
Reaction Steps
In a similar manner to Example 1, 6-[3,5-bis(trifluoromethyl)benzyl]-5,6,7,8,9,10-hexahydro-4-(2-methylphenyl)-2-(methylsulfonyl)-5-oxopyrimido[4,5-b][1,5]diazocine (Compound of Reference Example 19; 85.9 mg) was reacted with 3-(acetylamino)pyrrolidine (23.1 mg) to obtain 2-[3-(acetylamino)pyrrolidine-1-yl]-6-[3,5-bis(trifluoromethyl)benzyl]-5,6,7,8,9,10-hexahydro-4-(2-methylphenyl)-5-oxopyrimido[4,5-b][1,5]diazocine (92.6 mg, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064119B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-4e4c26b787c44bf9acb53e84cf39906f |
| Source note | uspto-grants-2006_06 |