Acetone → Rivaroxaban, Xarelto, BAY 59-7939
Reaction equation
[CH3:38][C:39](=[O:40])[CH3:41].[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[Cl:28][c:29]1[cH:30][cH:31][c:32]([C:34](=[O:35])[Cl:36])[s:33]1.[NH2:1][CH2:2][CH:3]1[CH2:4][N:5]([c:9]2[cH:10][cH:11][c:12]([N:15]3[C:16](=[O:21])[CH2:17][O:18][CH2:19][CH2:20]3)[cH:13][cH:14]2)[C:6](=[O:8])[O:7]1.[Na+:22].[Na+:23].[O-:24][C:25](=[O:26])[O-:27].[OH2:37]>>[NH:1]([CH2:2][CH:3]1[CH2:4][N:5]([c:9]2[cH:10][cH:11][c:12]([N:15]3[C:16](=[O:21])[CH2:17][O:18][CH2:19][CH2:20]3)[cH:13][cH:14]2)[C:6](=[O:8])[O:7]1)[C:34]([c:32]1[cH:31][cH:30][c:29]([Cl:28])[s:33]1)=[O:35]Participants
8
Sources & evidence
- ORD record
- ord-a11789d48664471bad3a687c614f2cbe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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