alpha-Chloro-o-xylene → 2-(2-methylphenylmethylthio)pyridine N-oxide
反応式
Cl[CH2:2][C:3]1[C:4]([CH3:9])=[CH:5][CH:6]=[CH:7][CH:8]=1.[Na].[SH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N+:13]=1[O-:18]>>[CH3:9][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[CH2:2][S:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N+:13]=1[O-:18]参加物
3
実験手順
The intermediate 2-(2-methylphenylmethylthio)-pyridine N-oxide is prepared by the procedure described in U.S. Pat. No. 3,960,542, Example 2 from α-chloro o-xylene and 2-mercaptopyridine N-oxide sodium salt. Melting point 134°–136° C. Yield 85% theory. Structure confirmed by IR and NMR.
出典と根拠
- ORDレコード
- ord-ee039937186d441294fc81a241a93334
- 出典データセット
- uspto-grants-2006_06
- 特許番号
- US07064139B2
反応ノート
読み込み中…