HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1829737Generated: November 4, 2026
Acetic Acid → 2-[(2,5-Dimethylphenyl)methanesulfonyl]-4-methyl-1-oxo-1lambda~5~-pyridine
https://huagongshe.com/reaction/1829737
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 2-{[(2,5-Dimethylphenyl)methyl]sulfanyl}-4-methyl-1-oxo-1lambda~5~-pyridine | HCID 13178743 | — |
| Catalyst | Sodium tungstate | HCID 26052 | — |
| Product | 2-[(2,5-Dimethylphenyl)methanesulfonyl]-4-methyl-1-oxo-1lambda~5~-pyridine | HCID 13178744 | — |
Reaction Steps
The sulfide isolated in step (a) above was dissolved in 20 ml of glacial acetic acid and 1.5 ml of 30% hydrogen peroxide was added along with 100 mg of sodium tungstate. The reaction mixture was heated at 40° C. for one hour, cooled, and poured into water to percipitate the product. Yield, 1.46 or 89%. NMR supported the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07064139B2 |
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| Source dataset | uspto-grants-2006_06 |
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| ORD ID | ord-931cc647bf224d12a8bd2c23f5789b52 |
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| Source note | uspto-grants-2006_06 |
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