HCID 69526653, compound → HCID 22054885, compound

Participants

Reaction Steps

To a solution of 5-(benzyloxy)-1-methyl-2-(2-phenylethenyl)-1H-indole (204 mg, 0.601 mmol) in EtOH (5 ml) and THF (5 ml) was added 10% palladium on carbon (50 mg). The resulting mixture was stirred under hydrogen (2 atm) for 15 h at room temperature. The mixture was filtered through Celite and washed with EtOH. The filtrate was concentrated in vacuo and then the residue was purified by silica gel (4.5 g) chromatography eluted with chloroform to give 1-methyl-2-(2-phenylethyl)-1H-indol-5-ol (110 mg, 72.8%).

Provenance & Evidence