tert-Butylsulfinamide, (S)-(-)- → HCID 71171587, compound

Participants

Reaction Steps

Preparation of (S)-t-butyl sulfinamide from (S)-2-Methyl-2-propylsulfinic acid (1R,2S)-1-phenyl-2-(4-toluenesulfonylamino)-propyl ester: The same procedure described above was followed, an furnished the title product in 86% yield and 96% ee. (HPLC, Chiralpak AS column, 90:10 hexane/ethanol; 1.2 mL/min, 222 nm; (R)-TBSA rt=6.6 min; (S)-TBSA, rt=9.4 min.). 1H NMR(CDCl3): δ 1.18 (s, 9H), 3.82 (br, s, 2H). 13C NMR (CDCl3): δ 22.1, 55.3.

Provenance & Evidence