HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanol → 3-chloro-4-(pyridin-3-ylmethoxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanol | HCID 7510 | — |
| Reactant | 4-Amino-2-chlorophenol | HCID 77578 | — |
| Reactant | 3-Chloro-4-(2-pyridylmethoxy)aniline | HCID 16781212 | — |
| Product | 3-chloro-4-(pyridin-3-ylmethoxy)aniline | HCID 16794144 | 51.4% |
Reaction Steps
Compound 2A (0.84 g, 51%) was prepared from 4-amino-2-chloro-phenol (1.0 g, 6.96 mmol), 3-hydroxymethylpyridine (1.52 g, 13.9 mmol) by a route analogous to that used for the preparation of 1C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064203B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-d705ea6b943c4f65a5ce3468b63f52f5 |
| Source note | uspto-grants-2006_06 |