3-chloro-4-(pyridin-3-ylmethoxy)aniline → HCID 21031525, compound

HRID 1829908Notes

Reaction equation

HRID 1829908 reaction equation
[C:1]([O:5][C:6](=[O:26])[NH:7][CH:8]1[CH2:13][CH2:12][N:11]([CH2:14][C:15]2[CH:16]=[CH:17][N:18]3[C:23]=2[C:22](SC)=[N:21][CH:20]=[N:19]3)[CH2:10][CH2:9]1)([CH3:4])([CH3:3])[CH3:2].[Cl:27][C:28]1[CH:29]=[C:30]([NH2:42])[CH:31]=[CH:32][C:33]=1[O:34][CH2:35][C:36]1[CH:37]=[N:38][CH:39]=[CH:40][CH:41]=1>>[C:1]([O:5][C:6](=[O:26])[NH:7][CH:8]1[CH2:13][CH2:12][N:11]([CH2:14][C:15]2[CH:16]=[CH:17][N:18]3[C:23]=2[C:22]([NH:42][C:30]2[CH:31]=[CH:32][C:33]([O:34][CH2:35][C:36]4[CH:37]=[N:38][CH:39]=[CH:40][CH:41]=4)=[C:28]([Cl:27])[CH:29]=2)=[N:21][CH:20]=[N:19]3)[CH2:10][CH2:9]1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 167941443-chloro-4-(pyridin-3-ylmethoxy)anilineHCID 21031527HCID 21031527, compound

Product 1

HCID 21031525HCID 21031525, compoundYield 61%

Procedure

Compound 2B (78 mg, 61%) was prepared from 1B (86 mg, 0.23 mmol) and 2A (86 mg, 0.37 mmol) by a route analogous to that used for the preparation of 1F (method one).

Sources & evidence

ORD record
ord-3a2009a5ad9d470f88796f2a305cf950
Source dataset
uspto-grants-2006_06
Patent number
US07064203B2

Reaction notes

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