HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorobenzylic alcohol → 3-Chloro-4-(3-fluorobenzyloxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorobenzylic alcohol | HCID 68008 | — |
| Reactant | 4-Amino-2-chlorophenol | HCID 77578 | — |
| Reactant | 3-Chloro-4-(2-pyridylmethoxy)aniline | HCID 16781212 | — |
| Product | 3-Chloro-4-(3-fluorobenzyloxy)aniline | HCID 7059263 | 88.8% |
Reaction Steps
Compound 3A (1.65 g, 78%) was prepared from 4-amino-2-chloro-phenol (1.06 g, 7.38 mmol), 3-fluorobenzyl alcohol (2.4 g, 16.8 mmol) by a route analogous to that used for the preparation of 1C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064203B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-dda033e088c94611a5eedb7bd12db514 |
| Source note | uspto-grants-2006_06 |