3-Chloro-4-(2-pyridylmethoxy)aniline → HCID 22055248, compound
Reaction equation
[C:1]1([CH2:11][OH:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1.[NH2:13][C:14]1[CH:19]=[CH:18][C:17](O)=[C:16]([Cl:21])[CH:15]=1.ClC1C=C(N)C=CC=1OCC1C=CC=CN=1>>[Cl:21][C:16]1[CH:15]=[C:14]([NH2:13])[CH:19]=[CH:18][C:17]=1[O:12][CH2:11][C:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1Participants
3
Procedure
Compound 11A was prepared from 4-amino-2-chloro-phenol 1-isoquinolinyl methanol by a route analogous to that used for the preparation of 1C.
Sources & evidence
- ORD record
- ord-219d76c33afc42be8511b42b9e7246e4
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07064203B2
Reaction notes
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