HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 135820113, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 1,3-Thiazole-2-carbaldehyde | HCID 2734903 | — |
| Reactant | HCID 135819873 | HCID 135819873 | — |
| Solvent | DCM MeOH AcOH | HCID 21877243 | — |
| Product | HCID 135820113 | HCID 135820113 | — |
Reaction Steps
3-Benzimidazol-2-yl-1H-indazole-5-ylamine (1 equivalent), 2-thiazolecarboxaldehyde(1.1 equivalent), BH3: pyridine (10 equivalents, 8 M in pyridine) in AcOH:MeOH:CH2Cl2 (1:2:2) were stirred for 18 hours at room temperature. The solvent was removed, and the residue was purified by preparatory HPLC. LC/MS (m/z) 347.1 (MH+), Rt 1.93 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064215B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-755e53049223423a8bd714a4fcfc0dd4 |
| Source note | uspto-grants-2006_06 |