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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1830017Generated: October 26, 2026

4-(3-Amino-4-methylamino-phenoxy)-pyridine-2-carboxylic acid methylamide → 4-[2-(5-Fluoro-1H-indazol-3-yl)-1-methyl-1H-benzimidazol-5-yloxy]-pyridine-2-carboxylic acid methylamide

https://huagongshe.com/reaction/1830017

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Amino-4-methylamino-phenoxy)-pyridine-2-carboxylic acid methylamideHCID 17755838—
ReactantHCID 178520032HCID 178520032—
Product4-[2-(5-Fluoro-1H-indazol-3-yl)-1-methyl-1H-benzimidazol-5-yloxy]-pyridine-2-carboxylic acid methylamideHCID 22056055—

Reaction Steps

The title compound was synthesized from 5-fluoro-1H-indazole-3-carbaldehyde and 4-(3-amino-4-methylamino-phenoxy)-pyridine-2-carboxylic acid methylamide as described above in Example 4. LC/MS (m/z) 417.4 (MH+), Rt 3.62 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07064215B2
Source datasetuspto-grants-2006_06
ORD IDord-fc17fdce28a04c7eaa4645b8d916b12a
Source noteuspto-grants-2006_06