HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → HCID 135819949, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 135820263 | HCID 135820263 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 135819949 | HCID 135819949 | — |
Reaction Steps
3-[6-(4-Methylpiperazin-1-yl)-1H-benzoimidazol-2-yl]-1H-indazol-4-ylamine is dissolved in CH2Cl2 and benzoyl chloride (1.1 equivalent) is added followed by diisopropylethylamine (1.1 equivalent). The resulting mixture is stirred overnight. The solution is then concentrated and the resulting residue is purified by preparatory HPLC to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064215B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-2acd01c9eb8945d4a74feb940380adb9 |
| Source note | uspto-grants-2006_06 |