HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → HCID 135819900, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 135820263 | HCID 135820263 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 135819900 | HCID 135819900 | — |
Reaction Steps
3-[6-(4-Methylpiperazin-1-yl)-1H-benzoimidazol-2-yl]-1H-indazol-4-ylamine (1 equivalent), methanesulfonyl chloride (1.1 equivalent), and diisopropylethylamine (2 equivalents) in CH2Cl2 are stirred for 18 hours. The solvent is evaporated, and the resulting residue is purified by preparatory HPLC to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064215B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-e4c6779be68b465e9c2b3441797fc712 |
| Source note | uspto-grants-2006_06 |