HCID 58650618, compound → HCID 178464023, compound
Reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([N:9]2[C@@H:14]([CH3:15])[CH2:13][O:12][C@H:11]([CH2:16][N:17]([CH2:20][CH3:21])[CH2:18][CH3:19])[CH2:10]2)[CH:5]=[CH:6][C:7]=1[NH2:8].[F:22][C:23]1[CH:31]=[C:30]2[C:26]([C:27]([CH:32]=O)=[N:28][NH:29]2)=[CH:25][CH:24]=1>>[F:22][C:23]1[CH:31]=[C:30]2[C:26]([C:27]([C:32]3[NH:8][C:7]4[CH:6]=[CH:5][C:4]([N:9]5[C@@H:14]([CH3:15])[CH2:13][O:12][C@H:11]([CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21])[CH2:10]5)=[CH:3][C:2]=4[N:1]=3)=[N:28][NH:29]2)=[CH:25][CH:24]=1Participants
3
Procedure
The title compund is synthesized according to the general procedure described in Example 4 with {[(2R,5S)-4-(3,4-diaminophenyl)-5-methylmorpholin-2-yl]methyl}diethylamine and 6-fluoro-1H-indazole-3-carbaldehyde.
Workup
- customThe title compund is synthesized
Sources & evidence
- ORD record
- ord-f85c8ffd221f41648bc3fba7693b06a4
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07064215B2
Reaction notes
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