1-[3-(Trifluoromethyl)pyridin-2-yl]piperazine → (RS)-1-Benzenesulfonyl-3-(2-chloro-phenyl)-4-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one

HRID 183004Notes

Reaction equation

HRID 183004 reaction equation
[F:26][C:27]([c:28]1[c:29]([N:34]2[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]2)[n:30][cH:31][cH:32][cH:33]1)([F:40])[F:41].[c:1]1([S:7](=[O:8])(=[O:9])[N:10]2[C:11](=[O:25])[N:12]([c:18]3[c:19]([Cl:24])[cH:20][cH:21][cH:22][cH:23]3)[CH:13]([C:15](=[O:16])[OH:17])[CH2:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([S:7](=[O:8])(=[O:9])[N:10]2[C:11](=[O:25])[N:12]([c:18]3[c:19]([Cl:24])[cH:20][cH:21][cH:22][cH:23]3)[CH:13]([C:15](=[O:16])[N:37]3[CH2:36][CH2:35][N:34]([c:29]4[c:28]([C:27]([F:26])([F:40])[F:41])[cH:33][cH:32][cH:31][n:30]4)[CH2:39][CH2:38]3)[CH2:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 27777861-[3-(Trifluoromethyl)pyridin-2-yl]piperazineHCID 67140727HCID 67140727, compound

Product 1

HCID 25029764(RS)-1-Benzenesulfonyl-3-(2-chloro-phenyl)-4-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one

Sources & evidence

ORD record
ord-f1aebdf084954bd1964337f39ac515a1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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