HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl[2-(pyridin-4-yl)ethyl]amine → 10-[(2'-Methoxy-2-methyl-[1,1'-biphenyl]-4-yl)-carbonyl]-N-methyl-N-[2-(pyridin-4-yl)ethyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl[2-(pyridin-4-yl)ethyl]amine | HCID 143276 | — |
| Reactant | 10-[(2'-methoxy-2-methyl-[1,1'-biphenyl]-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acid | HCID 10275813 | — |
| Product | 10-[(2'-Methoxy-2-methyl-[1,1'-biphenyl]-4-yl)-carbonyl]-N-methyl-N-[2-(pyridin-4-yl)ethyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxamide | HCID 10231632 | — |
Reaction Steps
Prepared by treatment of 10-[(2′-methoxy-2-methyl-[1,1′-biphenyl]-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acid of Step E, with 4-(2-methylaminoethyl)pyridine (1.2 equiv.) in the manner of Example 5, Step E.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064120B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-bed0df5a93324fb494deae1ca276a5b6 |
| Source note | uspto-grants-2006_06 |