Benzyl Bromide → 1-Bromo-4-phenylmethoxybenzene

Participants

Reaction Steps

4-Bromophenol (100 g, 0.587 mol) was dissolved in acetone (1,100 ml) and after adding thereto in sequence anhydrous potassium carbonate (159.53 g, 1.156 mmol) and benzyl bromide (103.78 g, 0.607 mol), the solution was refluxed under heating for 3 hours. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure. The obtained crude product was recrystallized (the recrystallization operation was performed using hexane as a solvent) to obtain the titled compound (120.76 g, 0.459 mol, 79%).

Provenance & Evidence