3-Fluorobenzenesulfonyl Chloride → N-{3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-3-fluorobenzenesulfonamide
Reaction equation
[Cl:1][c:2]1[n:3][c:4](-[c:5]2[s:6][c:7]([CH:8]([CH3:9])[CH3:10])[n:11][c:12]2-[c:13]2[cH:14][c:15]([NH:16][S:17]([c:18]3[c:19]([F:20])[cH:21][cH:22][cH:23][c:24]3[F:25])(=[O:26])=[O:27])[cH:28][cH:29][cH:30]2)[cH:31][cH:32][n:33]1.[F:58][c:59]1[cH:60][c:61]([S:65](=[O:66])(=[O:67])[Cl:68])[cH:62][cH:63][cH:64]1.[NH2:34][c:35]1[c:36]([F:57])[c:37](-[c:41]2[n:42][c:43]([C:53]([CH3:54])([CH3:55])[CH3:56])[s:44][c:45]2-[c:46]2[n:47][c:48]([NH2:52])[n:49][cH:50][cH:51]2)[cH:38][cH:39][cH:40]1>>[NH:34]([c:35]1[c:36]([F:57])[c:37](-[c:41]2[n:42][c:43]([C:53]([CH3:54])([CH3:55])[CH3:56])[s:44][c:45]2-[c:46]2[n:47][c:48]([NH2:52])[n:49][cH:50][cH:51]2)[cH:38][cH:39][cH:40]1)[S:65]([c:61]1[cH:60][c:59]([F:58])[cH:64][cH:63][cH:62]1)(=[O:66])=[O:67]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-1a07ff692c804632bfc9c9fc3e6bd261
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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