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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18303Generated: October 25, 2026

Ethyl indole-2-carboxylate → 6-methoxy-1-methyl-1H-indole

https://huagongshe.com/reaction/18303

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl indole-2-carboxylateHCID 73125—
Reactant6-Methoxy-1H-indoleHCID 76659—
Product6-methoxy-1-methyl-1H-indoleHCID 477792995%

Reaction Steps

According to the procedure of Preparation 9 (a), except substituting 6-methoxy-1H-indole for the ethyl indole-2-carboxylate, the title compound (2.3 g, 95%) was obtained as an oil: MS (ES) m/e 162.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07741339B2
Source datasetuspto-grants-2010_06
ORD IDord-7fed0579a32d43daaab0b280d92f1751
Source noteuspto-grants-2010_06