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Chlorosuccinimide → 2-Amino-5-Chloro-alpha-(Methoxyimino)-4-Thiazoleacetic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chlorosuccinimide | HCID 31398 | — |
| 反応物 | 2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid | HCID 125216 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 2-Amino-5-Chloro-alpha-(Methoxyimino)-4-Thiazoleacetic Acid | HCID 54009366 | — |
反応手順
To 500 mL of DMF were added 50.0 g (250 mmol) of 2-amino-α-(methoxyimino)-4-thiazoleacetic acid and 35 g (260 mmol) of N-chlorosuccinimide. The mixture was stirred at room temperature overnight, after which time mass spectral analysis showed no more starting material to be present. The light brown solution was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07067482B2 |
| 出典データセット | uspto-grants-2006_06 |
| ORD ID | ord-d9eacd7f5c91419790288eb60b321ec9 |
| 出典メモ | uspto-grants-2006_06 |