Boron tribromide → HCID 10236706, compound

Participants

Reaction Steps

The title compound was prepared by reacting 1,5-dichloro-8-fluoro-6-(4-methoxyphenyl)-2-naphthol (0.15 g, 0.445 mmol) with boron tribromide (0.67 mL of 1N solution, 0.67 mmol) according to method D to yield 0.12 g (83%) of a light yellow solid mp 206–216° C.; 1H NMR (DMSO-d6): δ 6.88 (2H, d, J=8.55 Hz), 7.34–7.39 (3H, m), 7.51 (1H, d, J=9.34 Hz), 8.21 (1H, dd, J=1.66 Hz, J=9.34 Hz), 9.74 (1H, bs), 10.99 (1H, bs); MS (ESI) m/z 321/323/326 (M−H)−.

Provenance & Evidence