HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylbenzylamine → N-benzyl-(3-methoxy-4-nitro-benzyl)-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylbenzylamine | HCID 7669 | — |
| Reactant | 3-Methoxy-4-nitrobenzyl bromide | HCID 12621604 | — |
| Product | N-benzyl-(3-methoxy-4-nitro-benzyl)-methyl-amine | HCID 22046408 | — |
Reaction Steps
A solution of N-methyl-benzyl amine was alkylated with 3-methoxy-4-nitro-benzyl bromide as described above for compound 338. 1H NMR (400 MHz, CDCl3): δ7.83 (d, J=8.6 Hz, 1H), 7.35 (s, 4H), 7.26 (s, 1H), 7.17 (s, 1H), 7.01 (d, J=7.04 Hz, 1H), 3.97 (s, 3H), 3.55 (s, 4H), 2.22 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067506B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-4c70838f4edf422398141475864e47d9 |
| Source note | uspto-grants-2006_06 |