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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1830810Generated: November 1, 2026

HCID 22048475, compound → HCID 22048489, compound

https://huagongshe.com/reaction/1830810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22048475HCID 22048475—
CatalystManganese dioxideHCID 14801—
SolventChloroformHCID 6212—
ProductHCID 22048489HCID 2204848982.7%

Reaction Steps

A mixture of (intermediate 24) (0.0382 mol) and MnO2 (28 g) in trichloromethane (200 ml) was stirred and refluxed overnight. The mixture was cooled to room temperature, filtered over celite and the solvent was evaporated till dryness. The product was used without further purification, yielding 11.5 g (82.7%) of [4-(3-chlorophenyl)-2-methoxy-6-quinolinyl]-3-furanyl-methanone (intermediate 25).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067531B2
Source datasetuspto-grants-2006_06
ORD IDord-7857bdfd8cde4753b94f08084168c372
Source noteuspto-grants-2006_06