HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22048475, compound → HCID 22048489, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22048475 | HCID 22048475 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 22048489 | HCID 22048489 | 82.7% |
Reaction Steps
A mixture of (intermediate 24) (0.0382 mol) and MnO2 (28 g) in trichloromethane (200 ml) was stirred and refluxed overnight. The mixture was cooled to room temperature, filtered over celite and the solvent was evaporated till dryness. The product was used without further purification, yielding 11.5 g (82.7%) of [4-(3-chlorophenyl)-2-methoxy-6-quinolinyl]-3-furanyl-methanone (intermediate 25).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067531B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-7857bdfd8cde4753b94f08084168c372 |
| Source note | uspto-grants-2006_06 |