Ammonia → p-Cyanobenzamide

HRID 1830875Notes

Reaction equation

HRID 1830875 reaction equation
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7](Cl)=[O:8])=[CH:5][CH:4]=1)#[N:2].[NH3:12]>>[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([NH2:12])=[O:8])=[CH:5][CH:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 801724-Cyanobenzoyl chloride

Product 1

HCID 76427p-Cyanobenzamide

Procedure

By the reaction in the same manner as in Example 25-i) using 4-cyanobenzoyl chloride (5.30 g) and 28% aqueous ammonia (20 ml), the title compound (3.62 g) was obtained by pale-brown needle crystals.

Workup

  1. customBy the reaction in the same manner as in Example 25-i)

Sources & evidence

ORD record
ord-65e651092e5b45de905a10912bb9ede5
Source dataset
uspto-grants-2006_06
Patent number
US07067537B2

Reaction notes

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