Pyridine-2-carbothioamide → HCID 22049807, compound

HRID 1830885Notes

Reaction equation

HRID 1830885 reaction equation
Br[CH2:2][C:3]([C:5]1[CH:6]=[N:7][CH:8]=[CH:9][C:10]=1[CH3:11])=O.[N:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:18](=[S:20])[NH2:19]>>[CH3:11][C:10]1[CH:9]=[CH:8][N:7]=[CH:6][C:5]=1[C:3]1[N:19]=[C:18]([C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][N:12]=2)[S:20][CH:2]=1

Participants

3

Reactant 2

HCID 1549499Pyridine-2-carbothioamideHCID 220497832-Bromo-1-(4-methylpyridin-3-yl)ethan-1-one

Product 1

HCID 22049807HCID 22049807, compoundYield 23.3%

Procedure

By the reaction in the same manner as in Example 25-iii) using 2-bromo-1-(4-methylpyridin-3-yl)ethanone hydrobromate (446 mg) and pyridine-2-carbothioamide (157 mg), the title compound (67 mg) was obtained as pale-red powder crystals.

Workup

  1. customBy the reaction in the same manner as in Example 25-iii)

Sources & evidence

ORD record
ord-e4c35bb206df4686a5f5ff00e32ec609
Source dataset
uspto-grants-2006_06
Patent number
US07067537B2

Reaction notes

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