5-Bromo-N-ethylpyridine-3-carboxamide → HCID 22049754, compound

HRID 1830890Notes

Reaction equation

HRID 1830890 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:12]=1)[C:7]([NH:9][CH2:10][CH3:11])=[O:8].[Cu](C#N)[C:14]#[N:15]>>[C:14]([C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:12]=1)[C:7]([NH:9][CH2:10][CH3:11])=[O:8])#[N:15]

Participants

3

Reactant 2

HCID 220497285-Bromo-N-ethylpyridine-3-carboxamideHCID 178418260HCID 178418260, compound

Product 1

HCID 22049754HCID 22049754, compoundYield 31.8%

Procedure

By the reaction in the same manner as in Example 42-ii) using 5-bromo-N-ethylnicotinamide (580 mg) and copper cyanide (350 mg), the title compound (141 mg) was obtained as colorless powder crystals.

Workup

  1. customBy the reaction in the same manner as in Example 42-ii)

Sources & evidence

ORD record
ord-efbc557ad97b47129fa512d6b680741a
Source dataset
uspto-grants-2006_06
Patent number
US07067537B2

Reaction notes

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