2-Bromo-1-(pyridin-4-yl)ethanone → HCID 22049801, compound

HRID 1830920Notes

Reaction equation

HRID 1830920 reaction equation
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=1)=O.[CH3:11][C:12]1[CH:17]=[CH:16][N:15]=[CH:14][C:13]=1[C:18](=[S:20])[NH2:19]>>[CH3:11][C:12]1[CH:17]=[CH:16][N:15]=[CH:14][C:13]=1[C:18]1[S:20][CH:2]=[C:3]([C:5]2[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=2)[N:19]=1

Participants

3

Reactant 2

HCID 4070312-Bromo-1-(pyridin-4-yl)ethanoneHCID 220497214-Methylpyridine-3-carbothioamide

Product 1

HCID 22049801HCID 22049801, compoundYield 24%

Procedure

By the reaction in the same manner as in Example 25-iii) using 2-bromo-1-(pyridin-4-yl)ethanone hydrobromate (460 mg) and 4-methylpyridine-3-thiocarboxamide (248 mg), the title compound (99 mg) was obtained as colorless powder crystals.

Workup

  1. customBy the reaction in the same manner as in Example 25-iii)

Sources & evidence

ORD record
ord-758feabc9c8c4bb296c5fe2a4e37c923
Source dataset
uspto-grants-2006_06
Patent number
US07067537B2

Reaction notes

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