HCID 22049679, compound → HCID 22049771, compound

HRID 1830921Notes

Reaction equation

HRID 1830921 reaction equation
Br[CH2:2][C:3]([C:5]1[CH:6]=[C:7]([CH:13]=[CH:14][CH:15]=1)[C:8]([O:10][CH2:11][CH3:12])=[O:9])=O.[CH3:16][C:17]1[CH:22]=[CH:21][N:20]=[CH:19][C:18]=1[C:23](=[S:25])[NH2:24]>>[CH3:16][C:17]1[CH:22]=[CH:21][N:20]=[CH:19][C:18]=1[C:23]1[S:25][CH:2]=[C:3]([C:5]2[CH:6]=[C:7]([CH:13]=[CH:14][CH:15]=2)[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:24]=1

Participants

3

Reactant 2

HCID 22049679HCID 22049679, compoundHCID 220497214-Methylpyridine-3-carbothioamide

Product 1

HCID 22049771HCID 22049771, compoundYield 37.6%

Procedure

By the reaction in the same manner as in Example 25-iii) using ethyl 3-(bromoacetyl)benzoate (18.10 g) and 4-methylpyridine-3-thiocarboxamide (8.11 g), the title compound (6.50 g) was obtained as pale-yellow powder crystals.

Workup

  1. customBy the reaction in the same manner as in Example 25-iii)

Sources & evidence

ORD record
ord-2b7b183e81d64425bb0c334e1bbcbfb2
Source dataset
uspto-grants-2006_06
Patent number
US07067537B2

Reaction notes

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