HCID 22049771, compound → HCID 22049703, compound

HRID 1830922Notes

Reaction equation

HRID 1830922 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[C:8]1[S:9][CH:10]=[C:11]([C:13]2[CH:14]=[C:15]([CH:21]=[CH:22][CH:23]=2)[C:16]([O:18]CC)=[O:17])[N:12]=1>[OH-].[Na+]>[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[C:8]1[S:9][CH:10]=[C:11]([C:13]2[CH:14]=[C:15]([CH:21]=[CH:22][CH:23]=2)[C:16]([OH:18])=[O:17])[N:12]=1

Participants

3

Reactant 1

HCID 22049771HCID 22049771, compound

Product 1

HCID 22049703HCID 22049703, compoundYield 88.8%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

By the reaction in the same manner as in Example 77 using ethyl 3-[2-(4-methylpyridin-3-yl)-1,3-thiazol-4-yl]benzoate (6.50 g) and 1N NaOH (80 ml), the title compound (5.27 g) was obtained as a colorless powder.

Sources & evidence

ORD record
ord-f27688ac2dfe4d7da54a4744f8d21094
Source dataset
uspto-grants-2006_06
Patent number
US07067537B2

Reaction notes

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