4-Fluorobenzoyl chloride → HCID 178522257, compound
Reaction equation
[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.ClC1C=CC(C([NH:18][C:19]2[CH:20]=[N:21][C:22]([OH:25])=[CH:23][CH:24]=2)=O)=CC=1>>[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:18][C:19]2[CH:20]=[N:21][C:22]([OH:25])=[CH:23][CH:24]=2)=[O:7])=[CH:4][CH:3]=1Participants
3
Procedure
Starting from 4-fluorobenzoyl chloride (1.59 g, 10.0 mmol) and using the procedure as described for the preparation of 4-Chloro-N-(6-hydroxy-pyridin-3-yl)-benzamide yielded the title compound, which was used without further purification.
Sources & evidence
- ORD record
- ord-db4d242b9d7c4bafb8eef800a404141e
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07067517B2
Reaction notes
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