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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1831077Generated: October 25, 2026

Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester

https://huagongshe.com/reaction/1831077

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic chloride, N-methyl-N-phenyl-HCID 77969—
Reactant4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenolHCID 155241—
ProductMethyl-phenyl-carbamic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl esterHCID 10150601—

Reaction Steps

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was purified by preparative HPLC (36%, white crystals). HPLC-MS m/z=389.1 (M+1), Rt: 5.13 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067517B2
Source datasetuspto-grants-2006_06
ORD IDord-ac2b8a1458554d74b7f7c2d87439d629
Source noteuspto-grants-2006_06