Carbamic chloride, N-methyl-N-phenyl- → HCID 10172784, compound

HRID 1831082Notes

Reaction equation

HRID 1831082 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:16]=[CH:15][C:6]([O:7][C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.[CH3:19][N:20]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:21](Cl)=[O:22]>>[F:1][C:2]([F:17])([F:18])[C:3]1[CH:16]=[CH:15][C:6]([O:7][C:8]2[CH:9]=[CH:10][C:11]([O:14][C:21](=[O:22])[N:20]([CH3:19])[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)=[CH:12][CH:13]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 170230p-(4-(Trifluoromethyl)phenoxy)phenol

Product 1

HCID 10172784HCID 10172784, compound

Procedure

The title compound was prepared from 4-(4-trifluoromethyl-phenoxy)-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was purified by preparative HPLC (78%, white crystals). HPLC-MS m/z=388.0 (M+1), Rt: 5.59 min.

Workup

  1. customThe crude product was purified by preparative HPLC (78%, white crystals)

Sources & evidence

ORD record
ord-a588f2399fc7489abc38e2b8e38eefd7
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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