Carbamic chloride, N-methyl-N-phenyl- → HCID 10194625, compound

HRID 1831090Notes

Reaction equation

HRID 1831090 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]([C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=3)[S:11][CH:12]=2)=[CH:4][CH:3]=1.[CH3:20][N:21]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[C:22](Cl)=[O:23]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:9]=[C:10]([C:13]3[CH:18]=[CH:17][C:16]([O:19][C:22](=[O:23])[N:21]([CH3:20])[C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)=[CH:15][CH:14]=3)[S:11][CH:12]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 14738154-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]phenol

Product 1

HCID 10194625HCID 10194625, compound

Procedure

The title compound was prepared from 4-[4-(4-chloro-phenyl)-thiazol-2-yl]-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was recrystallized (ethanol/water) (59%, white crystals). HPLC-MS m/z=421.1 (M+1), Rt: 5.85 min

Workup

  1. customThe crude product was recrystallized (ethanol/water) (59%, white crystals)

Sources & evidence

ORD record
ord-5d830a4c20c34169aa993432f66379bd
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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