HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-2-(4-Hydroxy-phenyl)hexahydroisoindole-1,3-dione → cis-Methyl-phenyl-carbamic acid 4-(1,3-dioxo-octahydro-isoindol-2-yl)-phenyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-2-(4-Hydroxy-phenyl)hexahydroisoindole-1,3-dione | HCID 7035660 | — |
| Reactant | 1-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodide | HCID 10947884 | — |
| Product | cis-Methyl-phenyl-carbamic acid 4-(1,3-dioxo-octahydro-isoindol-2-yl)-phenyl ester | HCID 69518024 | 77.4% |
Reaction Steps
The title compound (293 mg, 77% yield, white crystals) was prepared from cis-2-(4-hydroxy-phenyl)hexahydroisoindole-1,3-dione (245 mg, 1.00 mmol) and 1-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodide (343 mg, 1.00 mmol). HPLC-MS m/z=379 (M+1); Rt=4.08 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067517B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-ab5c04485f554859b47360451ba201a8 |
| Source note | uspto-grants-2006_06 |