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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1831132Generated: November 1, 2026

4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol → HCID 23636022, compound

https://huagongshe.com/reaction/1831132

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenolHCID 155241—
ReactantHCID 43145415HCID 43145415—
ProductHCID 23636022HCID 23636022—

Reaction Steps

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and 1-methyl-3-(2-methyl-piperidine-1-carbonyl)-3H-imidazol-1-ium iodide. The crude product was purified by flash chromatography using a Quad flash 25 (ethyl acetate/heptane (1:6), (71%, white crystals). HPLC-MS m/z=381.1 (M+1), Rt: 5.2 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067517B2
Source datasetuspto-grants-2006_06
ORD IDord-b96f28276e2e443caf29bb3815a37e1a
Source noteuspto-grants-2006_06