4-Morpholinecarbonyl chloride → HCID 23635767, compound

HRID 1831153Notes

Reaction equation

HRID 1831153 reaction equation
[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[N:17]1([C:23](Cl)=[O:24])[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][C:23]([N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[O:24])=[CH:12][CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 6208804-(3,5-Dichloro-pyridin-2-yloxy)-phenol

Product 1

HCID 23635767HCID 23635767, compound

Procedure

The title compound was prepared from 4-(3,5-dichloro-pyridin-2-yloxy)-phenol and morpholine-4-carbonyl chloride. The crude product was purified by preparative HPLC (45%, crystals. HPLC-MS m/z=369.1 (M+1), Rt: 4.3 min.

Workup

  1. customThe crude product was purified by preparative HPLC (45%, crystals

Sources & evidence

ORD record
ord-f12df9f8119b41658b768d3a2fecfa5e
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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