3-(3,4-dichloro-benzyl)-7-hydroxy-4-methyl-2H-chromen-2-one → Morpholine-4-carboxylic acid 3-(3,4-dichloro-benzyl)-4-methyl-2-oxo-2H-chromen-7-yl Ester

HRID 1831154Notes

Reaction equation

HRID 1831154 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:19]=[CH:20][C:21]=1[Cl:22])[CH2:5][C:6]1[C:7](=[O:18])[O:8][C:9]2[C:14]([C:15]=1[CH3:16])=[CH:13][CH:12]=[C:11]([OH:17])[CH:10]=2.[I-].[N:24]1([C:30](N2C=C[N+](C)=C2)=[O:31])[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:19]=[CH:20][C:21]=1[Cl:22])[CH2:5][C:6]1[C:7](=[O:18])[O:8][C:9]2[C:14]([C:15]=1[CH3:16])=[CH:13][CH:12]=[C:11]([O:17][C:30]([N:24]1[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1)=[O:31])[CH:10]=2

Participants

3

Reactant 2

HCID 59081453-(3,4-dichloro-benzyl)-7-hydroxy-4-methyl-2H-chromen-2-oneHCID 11220989223762-21-8

Product 1

HCID 86589205Morpholine-4-carboxylic acid 3-(3,4-dichloro-benzyl)-4-methyl-2-oxo-2H-chromen-7-yl Ester

Procedure

The title compound was prepared from 3-(3,4-dichloro-benzyl)-7-hydroxy-4-methyl-2H-chromen-2-one and 3-(morpholine-4-carbonyl)-1-methyl-3H-imidazol-1-ium iodide. HPLC-MS m/z=448 (M+1), Rt: 4.73 min.

Sources & evidence

ORD record
ord-667cce820cf14a9fa4bcec88386a8e59
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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