Carbamic chloride, N-methyl-N-phenyl- → 4-(Methyl-phenyl-carbamoyloxy)-benzoic Acid 2,5-dioxo-pyrrolidin-1-yl Ester

HRID 1831164Notes

Reaction equation

HRID 1831164 reaction equation
[O:1]=[C:2]1[CH2:6][CH2:5][C:4](=[O:7])[N:3]1[O:8][C:9](=[O:17])[C:10]1[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=1.[CH3:18][N:19]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:20](Cl)=[O:21]>>[O:7]=[C:4]1[CH2:5][CH2:6][C:2](=[O:1])[N:3]1[O:8][C:9](=[O:17])[C:10]1[CH:15]=[CH:14][C:13]([O:16][C:20](=[O:21])[N:19]([CH3:18])[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 15927810Succinimidyl-4-hydroxybenzoate

Product 1

HCID 865892064-(Methyl-phenyl-carbamoyloxy)-benzoic Acid 2,5-dioxo-pyrrolidin-1-yl Ester

Procedure

The title product was prepared from 4-Hydroxy-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester and N-methyl-N-phenylcarbamoyl chloride. The crude product was recrystallized from methanol (74%, white crystals).

Workup

  1. customThe crude product was recrystallized from methanol (74%, white crystals)

Sources & evidence

ORD record
ord-aa1ac4d245cd45b2aeeecd9e37339349
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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