Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid benzothiazol-2-yl Ester

HRID 1831178Notes

Reaction equation

HRID 1831178 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[OH:10].[CH3:11][N:12]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:13](Cl)=[O:14]>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[O:10][C:13](=[O:14])[N:12]([CH3:11])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 178517143HCID 178517143, compound

Product 1

HCID 69518823Methyl-phenyl-carbamic Acid benzothiazol-2-yl Ester

Procedure

The title product was prepared from 2-benzothiazolol and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC. (70%, white crystals). HPLC-MS: m/z=307.1 (M+1); Rt: 4.24 min, purity 85%.

Sources & evidence

ORD record
ord-42a5ecf81f4d4af4905d78eda45ea657
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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